Fonds documents the Mallochs' activities related to their medical and literary work. The fonds contains notes, correpondence, commonplace books, account books, material related to publications, family memorabilia, scrapbooks, photographs, telegrams, postcards and certificates.

The greater portion of these records consists of journals, cash books and ledgers recording purchases and sales, 1822-1898. Also included are formula and prescription books, catalogues, price lists, company releases, 1948 and 1952, and a genealogy of the Lyman Family in Canada.

The fonds contains Dr. Jacques' journal of medical accounts receivable entered in an account book issued with blank pages and bound in half suede with green cloth boards. The account book was kept between November 1879 and January 1881. A title handwritten on a paper label on the cover reads "Journal pour 1879-1880-1881." The author's full name comes from within the journal (L. A. George Jacques, M. D.) and from Lovell's Montreal directory for 1881-1882 (Louis A. George Jacques, M. D.). Laid in at p. 207 is an ink blotter featuring pharmaceutical advertising for Glyco-Heroin (Smith).

McDonald's correspondence, 1791-1860, mostly concerns business and property matters, but also includes personal correspondence. There are statements of account with McTavish, Frobisher & Co., 1799; with McTavish, Fraser & Co., 1803-1804; with McTavish, McGillivray & Co., 1808-1809. There are two volumes of autobiographical notes assembled in 1859 and covering the period 1791-1816.

There is a second copy of the autobiography, probably transcribed in the late 19th century. Written on the front fly leaf is the name: A.E. MacDonald. It has 63 leaves, and there are minor textual variants.

The fonds documents John Bell's activities related to his medical studies at McGill in Surgery, Materia Medica and the Institutes of Medicine, as well as his work as a private physician in Montreal. The fonds consists of notebooks, a photocopy of his MS McGill medical thesis, letters from his personal and professional life, one of his medical kits, receipts from merchants, various subscriptions, societies and clubs. The fonds also contains various reprints of Bell's articles, including the 1878 article, "Case of Diphtheria, Acute Laryngeal Symptoms", as well as the City of Montreal's "Mortality of Montreal" – a list of all deaths in Montreal in January 1878.

These McGill papers are entirely concerned with his property and estate. They comprise legal documents and copies of letters (some in McGill's hand) concerning his land holdings on St. Paul St., Montréal, in Stanbridge, and in Detroit. McGill's cash book, 1809-1815, and copy by W.D. Lighthall of a deed of conveyance to McGill of some land formerly occupied by the city fortifications, 1805, are also included, as is a blue-print and sketch by W.D. Lighthall of the site of McGill's St. Paul St. house. Estate papers comprise a probate of McGill's will, copied by Alice Lighthall, and his executor's cash book.

The company's records contain administrative, financial and publicity material. The administrative series comprises the minutes of the directors from 1929 to 1955 and of the executive committee from 1949 to 1956. An engagement book records contracts between the company and its employees, 1902-1906. Henry Morgan's business correspondence covers the period 1847-1850, and includes a few personal letters to his brother James. Financial records cover both internal operations and stock transactions. The former are documented by an account book, 1845-1848; ledgers, 1870-1889; and diaries, 1884, 1936; the latter by lists of stock holders, 1954-1960; and records of transfers of Morgan's common stock, 1954-1961. Also included are files of invoices, receipts and cheques, 1846-1852. Publicity materials largely centre around anniversaries. Scrapbooks of newspaper clippings, other printed materials and photographs cover the years 1936-1945, culminating in the company's centennial, for which a typescript history was prepared.

Fonds documents Frederick Augusutus Rees' activities as a physician in Bermuda. The fonds contains a ledger, an index to the ledger, notes and letters.