The content of the fonds includes letters, photographs, and official documents surrounding the Norman Bethune McGill-China Professorship Exchange at Peking Medical College, in addition to medical pamphlets, typed addresses, several commemorative Norman Bethune items. There are various Chinese tourist brochures and maps that McGregor collected during his travels in China, as well as newspaper clippings, reprints, and copies of articles collected by McGregor about China and medicine in the mid-1970s.

The fonds consists of textual records including proposal letters, guidelines, budget documents, and the six original VHS tapes made in 1984-85. Preservation copies of DVDs and mp4s made in 2016 are also included.

A large portion of the collection is concerned with the growth of the Medical Library at McGill. Other than the Catalogue of Books from the Library of the Medical Faculty of McGill College which dates from 1845, the earliest preserved records are the handwritten Library Committee reports of Dr. Francis Shepherd, dating from 1880. The textual material includes early library reports, surveys, information about library staff, finance, gifts, procedures, as well as information regarding the Osler Library and departmental building plans and renovations. The collection also includes correspondence, notes, photographs, and artifacts associated with 'McGill Medical Men' including: James "King" Cook, Robert Palmer Howard, William Wright, Robert Lea MacDonnell, Richard Lea MacDonnell, Herbert Stanley Birkett, and others. There are many reprints in the collection – some bound into volumes, and many that include signatures and written notes. The collection also includes photographs, scrapbooks, and glass lantern slides (some of which are from World War One), books, and theses. The Medical Library's accession records, index cards, and journal cards are also preserved in the collection, still housed in their original catalogue drawers (see Series 7). The collection includes various announcements, university calendars and directories related to the Faculty of Medicine, as well as communication, meeting minutes, and essays belonging to the McGill Medical Society (1884-1907), the McGill Reporting Society (1926-1951), and the Montreal Dermatological Society (1930-1951). Lastly, the collection includes miscellaneous textual materials related to McGill and the Faculty of Medicine, for instance McGill student attendance cards from 1828-1872 (with course name and professor details).

The fonds contains the manuscript of his book William Osler : A Life in Medicine.

Fonds contains the correspondence of James Bruce, Lord Eighth Earl of Elgin, with Dr. Michael McCulloch concerning his wife's confinements.

Fonds consists of 2 volumes of meeting minutes.

The fonds contains ledgers, legal documents, permits, one scrapbook, and photographs.

The fond consists of artifacts, bound volumes, photographs, and records from the Montreal Medico-Chirurgical Society. Included are correspondence, minute books, reports, monthly bulletins, a register of members, memorabilia, and albums of clippings and photographs.