The collection contains the Holmes Gold Medal, photographs, certificates, a poem, letters, newspaper clippings and memoirs.

The fonds contains chiefly of family correspondence between members of the Penfield and Chester families, as well as clippings and correspondence regarding Wilder Penfield's autobiography "No Man Alone" and correspondence regarding posthumous honours for Wilder Penfield. Family correspondence includes a 1917 letter from Helen Kermott (later Helen Kermott Penfield) accepting Wilder Penfield's marriage proposal. Much of the family correspondence is between Wilder and Helen Penfield and their daughter Priscilla and her husband William M. (Bill) Chester Jr., as well as Bill Chester's parents William (Sr.) and Alice Chester. There are incoming letters and many carbon copies of outgoing letters. A series of 1949 letters congratulates the young couple (Bill Chester and Priscilla Penfield) on their engagement. One letter is also between Wilder Penfield and George Chester. A few materials are related to posthumous honours for Wilder Penfield, such as the naming of a building after him at John Abbott College (letter to Wilder Penfield Jr.) and a 1982 speech given by Priscilla at the Penfield Children's Center (typescript copy). There is also correspondence between Bill Chester and William Feindel. One 1976 carbon copy of a letter (1976) details the period following the death of Priscilla's father, Wilder Penfield, while the couple was in Japan. Materials related to "No Man Alone" include clippings from journals and newspapers of reviews and book announcements, as well as two copies of the book jacket and some related correspondence.

Fonds documents Dr. Lella's research activities while at McGill.

The fonds consists of professional correspondence between J. G. Stratford and colleagues from the MGH, Montreal Neurological Institute, University of Saskatchewan, and the Osler Society. It also includes personal research material on pain (the causes and treatments), original drafts of his various publications (1953-2007), Montreal General Hospital daily journals (1966-1998), and some patient files (1943-1972, file 33). Stratford's bachelors, masters, and medical degrees from McGill University, as well as various professional certificates awarded to Stratford throughout his career are included in the fonds. Additional items include portraits and group photographs from the Neurological Department at Saskatchewan and the Montreal Neurological Institute, several brain scan prints, architectural blueprints of the Montreal General Hospital and Montreal Neurological Institute, as well as letters between Joseph & Aurelie Stratford and their close friends, Wilder & Helen Penfield.

Fonds documents Dr. J.C. Meakins' professional activities.

Fonds documents John Thomas Basken's activities as a medical student. The fonds contains admission cards, certificates and one oath.

Fonds contains various certificates and awards received by Browne; photographs and slides; two official portraits; letters of Ms. W. Browne (sister) regarding Browne; Last Will and Testament; The Canadian Medical Hall of Fame Induction Ceremony VHS, and newspaper clippings.

Fonds contains John Symonds' student notebook volume 3 of Dr. John Rutherford's clinical lectures for the year 1753 at the Royal Infirmary of Edinburgh. It was transcribed by Symonds in 1762.

The fonds consists of John Rowand's manuscript notebooks of lectures in medicine at the University of Edinburgh, 1780-1782. The material is divided into 4 folders: 1. Dr. Alexander Monro on surgery; 2. Dr. Andrew Duncan on the Practice of medicine; 3. Dr. William Irvine's chemical lectures vol. 1; 4. Dr. William Irvine's chemical lectures vol. 2.

The collection contains a photo album of classmates and Annie Hall, and three diplomas McGill MD, CM 1891, Ontario College of Physicians and Surgeons, 1891, and the Quebec College of Physicians and Surgeons 1892.