The fonds consists of books, letters, documents, drafts, publications, photographs, and several artifacts collected by W. W. Francis and Marian Francis Kelen over the course of their lifetimes. Many books and documents relate to Sir William Osler and the Osler family including several personal letters, the Deed of Trust documents regarding the Bibliotheca Osleriana, drafts of Osler's works, and a wooden travelling trunk that belonged to Edward Revere Osler. The fonds also includes original poetry written by Marian Osborne, W. W. Francis, and Marian Francis Kelen.

The fonds contains chiefly of family correspondence between members of the Penfield and Chester families, as well as clippings and correspondence regarding Wilder Penfield's autobiography "No Man Alone" and correspondence regarding posthumous honours for Wilder Penfield. Family correspondence includes a 1917 letter from Helen Kermott (later Helen Kermott Penfield) accepting Wilder Penfield's marriage proposal. Much of the family correspondence is between Wilder and Helen Penfield and their daughter Priscilla and her husband William M. (Bill) Chester Jr., as well as Bill Chester's parents William (Sr.) and Alice Chester. There are incoming letters and many carbon copies of outgoing letters. A series of 1949 letters congratulates the young couple (Bill Chester and Priscilla Penfield) on their engagement. One letter is also between Wilder Penfield and George Chester. A few materials are related to posthumous honours for Wilder Penfield, such as the naming of a building after him at John Abbott College (letter to Wilder Penfield Jr.) and a 1982 speech given by Priscilla at the Penfield Children's Center (typescript copy). There is also correspondence between Bill Chester and William Feindel. One 1976 carbon copy of a letter (1976) details the period following the death of Priscilla's father, Wilder Penfield, while the couple was in Japan. Materials related to "No Man Alone" include clippings from journals and newspapers of reviews and book announcements, as well as two copies of the book jacket and some related correspondence.

Family correspondence chiefly from 1763 to 1820 and family history documents.

This collection consists of 15 autograph letters between a sender who is only identified by the initials "J.T." and a Miss Fanny Caulfield. Also included is a love letter by Irish poet J. Finnerty, dated 1852.

This collection consists of translations from Terence, begun in 1778, and correspondence on military, political and private matters, 1787-1821, mostly addressed to Thomas Coutts, banker.

This file contains a letter from Anne Lawford recounting news of acquaintances and well-wishes for Christmas and the New Year, addressed to Anne's cousin, Reverend Jacob Low of Brockville, mentioning her son John Bowring Lawford.

The series consists of Dorothy Duncan’s personal and professional correspondence. The personal correspondence includes a significant number of letters from Duncan’s husband, Hugh MacLennan, as well as letters from family and friends. The professional correspondence is comprised of fan mail, exchanges with Duncan’s publishers, sample contracts, newsletters, and letters from other writers. Duncan’s correspondents included Stephen Leacock, Lorne Pierce, Robert J.C. Stead, Bruce Hutchinson, Gwethalyn Graham, David Walker, and C.P. Snow. This series also contains a file about graphology which is made up of reference material and several handwriting assessments by Robert H. Simmons.

This collection reflects Henry S. Chapman's relationships with a number of important figures in Montreal's political and business history, between roughly 1833 and 1853, the period following Chapman's return to London. A significant amount of the material in this collection is related to the 1837-1838 Upper and Lower Canada Rebellions (especially in Montreal), as well as events occurring immediately after the uprisings.

Consists of copies of original material, chiefly correspondence, arranged roughly by date. The contents of letters (1835-1853) include business partnerships, political reform, and personal news. Significant correspondents include Louis-Joseph Papineau, Louis-Hippolyte La Fontaine, Jacob Dewitt, François-Antoine Larocque (of Laroque and Bernard), Joseph Perreault, and Edmund Bailey O’Callaghan. There is also a partial manuscript on Canadian history and pages from a scrapbook, both dating from the 1830s.

The papers of "Jackrabbit" Johannsen reflect his personal, professional and recreational activities, mainly between 1934 and 1985. The largest part of the papers consists of correspondence with friends and organizations, particularly relating to skiing and outdoor life. Family relations are also covered. A series of brief journals provides a record of some of his daily activities, from 1948 to 1984. The remainder of the fonds include publications about Johannsen, photographs, maps and personal documents such as passports.