Fonds contains notes taken by Thomas McCrae between 1897 and 1904 at William Osler's clinics at the Johns Hopkins Hospital, Baltimore.

Fonds shows the relationship between Thomas R. Boggs and William Henry Welch, one of the founders in the establishment of the Johns Hopkins Medical School in Baltimore. The fonds contains letters from Welch to Boggs, from 1910 to 1927 concerning A Century of Charades, a book of riddles by William Bellamy.

Fonds shows Thomas W. Reynolds' activities as a medical student through his admission tickets for his complete medical formation. It contains 39 admission cards signed by or printed for the teachers, among them William Osler.

The fonds includes a copy of No. 3 Canadian General Hospital (McGill), 1914-1919 owned by Walter de M. Scriver and ephemera relating to Canadian General Hospital No. 3. It also contains a handwritten poem entitled "Tune of T'anks," composed by Scriver for his family and dated France, 1915.

The Penfield fonds consists of over eighty metres of Penfield's personal and professional records dating from his childhood up until his death in 1976, including during his career at the Montreal Neurological Institute. The materials in the fonds include photographs, correspondence, manuscripts and drafts of publications and speeches, research notes, glass slides, bound reports, films, and academic gowns.

Fonds contains the letters of certification of William A. De Wolf Smith's attendance at medical courses at McGill University in 1883. The fonds includes three letters of certification signed by teachers.

The fonds contains two sketchbooks of coloured sketches and shows William Arthur Johnson's activities in natural sciences and microscope work.

The fonds contains letters, 1948-1958, to and from Dr. W.W. Francis. It also includes two poems by Francis, and a letter from the Dean of the Faculty of Medicine regarding death of Francis in 1959.