The greater portion of these records consists of journals, cash books and ledgers recording purchases and sales, 1822-1898. Also included are formula and prescription books, catalogues, price lists, company releases, 1948 and 1952, and a genealogy of the Lyman Family in Canada.

The Sir William Osler Collection, distinct from the Bibliotheca, is an extensive archival holding of Osler's correspondence (including eighteen hundred original letters), daybooks, accounts, engagement books, legal documents, book invoices, membership certificates, notebooks, lectures, addresses, newspaper clippings, photographs, books with manuscript additions, and miscellaneous loose items formerly inserted into individual books in his library. The collection also contains various family papers, including correspondence of Lady Grace Revere Osler and Edward Revere Osler.

McDonald's correspondence, 1791-1860, mostly concerns business and property matters, but also includes personal correspondence. There are statements of account with McTavish, Frobisher & Co., 1799; with McTavish, Fraser & Co., 1803-1804; with McTavish, McGillivray & Co., 1808-1809. There are two volumes of autobiographical notes assembled in 1859 and covering the period 1791-1816.

There is a second copy of the autobiography, probably transcribed in the late 19th century. Written on the front fly leaf is the name: A.E. MacDonald. It has 63 leaves, and there are minor textual variants.

These McGill papers are entirely concerned with his property and estate. They comprise legal documents and copies of letters (some in McGill's hand) concerning his land holdings on St. Paul St., Montréal, in Stanbridge, and in Detroit. McGill's cash book, 1809-1815, and copy by W.D. Lighthall of a deed of conveyance to McGill of some land formerly occupied by the city fortifications, 1805, are also included, as is a blue-print and sketch by W.D. Lighthall of the site of McGill's St. Paul St. house. Estate papers comprise a probate of McGill's will, copied by Alice Lighthall, and his executor's cash book.

Fonds shows Dr. Allan McMillan's activities as a country doctor in the Eastern Townships of the end of the 19th century. |a The fonds consists of 6 daybooks separated into 6 vols.: v. 1: 22 Apr. 1876-18 Sept. 1885, v. 2: 22 Sept. 1885-7 March 1887, v. 3: 15 March 1894-24 Feb. 1897, v. 4: 1 Aug. 1898-30 June 1900, v. 5: 1 July 1900-8 June 1905, v. 6: 12 June 1905-14 July 1908.

Fonds documents the Mallochs' activities related to their medical and literary work. The fonds contains notes, correpondence, commonplace books, account books, material related to publications, family memorabilia, scrapbooks, photographs, telegrams, postcards and certificates.