Fonds documents Frederick Augusutus Rees' activities as a physician in Bermuda. The fonds contains a ledger, an index to the ledger, notes and letters.

The Sir William Osler Collection, distinct from the Bibliotheca, is an extensive archival holding of Osler's correspondence (including eighteen hundred original letters), daybooks, accounts, engagement books, legal documents, book invoices, membership certificates, notebooks, lectures, addresses, newspaper clippings, photographs, books with manuscript additions, and miscellaneous loose items formerly inserted into individual books in his library. The collection also contains various family papers, including correspondence of Lady Grace Revere Osler and Edward Revere Osler.

Fonds documents the Mallochs' activities related to their medical and literary work. The fonds contains notes, correpondence, commonplace books, account books, material related to publications, family memorabilia, scrapbooks, photographs, telegrams, postcards and certificates.

The fonds contains Dr. Jacques' journal of medical accounts receivable entered in an account book issued with blank pages and bound in half suede with green cloth boards. The account book was kept between November 1879 and January 1881. A title handwritten on a paper label on the cover reads "Journal pour 1879-1880-1881." The author's full name comes from within the journal (L. A. George Jacques, M. D.) and from Lovell's Montreal directory for 1881-1882 (Louis A. George Jacques, M. D.). Laid in at p. 207 is an ink blotter featuring pharmaceutical advertising for Glyco-Heroin (Smith).

Collection consists of six account books dating from the 1830s to the 1860s, including ledgers and daybooks, used and kept primarily by Enoch Curtis for his leather tanning business. There are also some loose accounts and notes on small sheets of paper. The ledgers use a single-entry bookkeeping method in £sd. They are organized by individual merchant account, with records of debits (purchases or expenditures made) and credits (payments or goods received). Parallel underlining and Xs indicate when an account has balanced. The collection also includes some records related to Stella Curtis from the 1890s, including one letter and two sheets of math problems marked Clarenceville Model School.

Collection contains two financial documents related to McGill College. The first is a memorandum between the College and its creditors in which the College agrees to pay out dividends and pay in installments towards the balance of the College's debt. It is signed by the individual creditors as well as by the principal of McGill College, Edmund A. Meredith. The memorandum contains a list of creditors of McGill College with their names and occupations listed, including William Lyman, druggist, Robert Abraham, printer, John Keller, merchant, and many others. A note dated 24 March 1847 with a response from representatives of the creditors is pasted on. The second document is a ledger sheet dated from 1844 to 1847 with the caption: "The Directors of McGill College to Joseph Hitchens."

Collection includes account book for the London Grand Junction Railway, London Dock Company and other engineering projects in England.

McDonald's correspondence, 1791-1860, mostly concerns business and property matters, but also includes personal correspondence. There are statements of account with McTavish, Frobisher & Co., 1799; with McTavish, Fraser & Co., 1803-1804; with McTavish, McGillivray & Co., 1808-1809. There are two volumes of autobiographical notes assembled in 1859 and covering the period 1791-1816.

There is a second copy of the autobiography, probably transcribed in the late 19th century. Written on the front fly leaf is the name: A.E. MacDonald. It has 63 leaves, and there are minor textual variants.

These McGill papers are entirely concerned with his property and estate. They comprise legal documents and copies of letters (some in McGill's hand) concerning his land holdings on St. Paul St., Montréal, in Stanbridge, and in Detroit. McGill's cash book, 1809-1815, and copy by W.D. Lighthall of a deed of conveyance to McGill of some land formerly occupied by the city fortifications, 1805, are also included, as is a blue-print and sketch by W.D. Lighthall of the site of McGill's St. Paul St. house. Estate papers comprise a probate of McGill's will, copied by Alice Lighthall, and his executor's cash book.