Collection consists of 36 autograph letters written to James Cameron and his son Archie. The correspondence includes letters by friends, associates, and members of the Cameron family in Toronto, Lake Beauport, Scotland, England, Hull, and Montreal. Subjects include family news, freemasonry, business (regarding deed of sales), factory work in Toronto, curling, and an April Fools' Day letter. With three extant envelopes.

The Sir William Osler Collection, distinct from the Bibliotheca, is an extensive archival holding of Osler's correspondence (including eighteen hundred original letters), daybooks, accounts, engagement books, legal documents, book invoices, membership certificates, notebooks, lectures, addresses, newspaper clippings, photographs, books with manuscript additions, and miscellaneous loose items formerly inserted into individual books in his library. The collection also contains various family papers, including correspondence of Lady Grace Revere Osler and Edward Revere Osler.

Three letters from Seaton relating to the Rebellion of 1837, including a letter to General Fitzroy Sommerset about the capture of St-Eustache.

This collection consists of translations from Terence, begun in 1778, and correspondence on military, political and private matters, 1787-1821, mostly addressed to Thomas Coutts, banker.

Consists of an English translation of a letter to the Marquis de la Jonquière written by Antoine-Louis Rouillé, comte de Jouy, secretary of state for the French Navy, at Versailles, dated 28 February 1750. The letter discusses an immediate release of prisoners of war taken during conflicts between the French and British colonies. It also includes a mention of Indigenous allies of England and France, and Indigenous people captured during the conflicts: "the Indian Prisoners among the two Nations be likewise released, but after all the French and English Prisoners are released" The letter also includes the name of examiner Josiah Willard, secretary of the province of Massachusetts-Bay.