The fonds illustrates Dr. Cone's work as a neurosurgeon and consists of correspondence, letters, articles, newspaper clippings, obituaries, photographs, slides, research material and notes, course material, annual reports, manuscripts, typescripts, annotations, published and unpublished manuscripts written by Dr. Cone, printed copies of articles, and patient files.

The Penfield fonds consists of over eighty metres of Penfield's personal and professional records dating from his childhood up until his death in 1976, including during his career at the Montreal Neurological Institute. The materials in the fonds include photographs, correspondence, manuscripts and drafts of publications and speeches, research notes, glass slides, bound reports, films, and academic gowns.

The fonds consists of professional correspondence between J. G. Stratford and colleagues from the MGH, Montreal Neurological Institute, University of Saskatchewan, and the Osler Society. It also includes personal research material on pain (the causes and treatments), original drafts of his various publications (1953-2007), Montreal General Hospital daily journals (1966-1998), and some patient files (1943-1972, file 33). Stratford's bachelors, masters, and medical degrees from McGill University, as well as various professional certificates awarded to Stratford throughout his career are included in the fonds. Additional items include portraits and group photographs from the Neurological Department at Saskatchewan and the Montreal Neurological Institute, several brain scan prints, architectural blueprints of the Montreal General Hospital and Montreal Neurological Institute, as well as letters between Joseph & Aurelie Stratford and their close friends, Wilder & Helen Penfield.

This collection is divided into material either by, or about, Wilder Graves Penfield. The material was collected by Lewis in order to write his biography. The fonds also includes materials associated with Mr. Lewis' writing of the biography.

The Penfield material is organized by family member, with the largest portion belonging to Wilder Penfield and his wife Helen Penfield. This material is largely personal in nature. It consists of originals and photocopies of diaries, as well as personal correspondence between Penfield and his wife, family photographs, and ephemera from a variety of social and professional events. There is also a small selection of personal correspondence between family members.

Lewis created drafts, revisions, letters concerning the development of the screenplay, and research material. Correspondence between Lewis and the family is contained in the material covering personal family matters.

The fonds illustrates Dr. McNaughton’s work as a neurosurgeon and consists of correspondence, letters, articles, newspaper clippings, obituaries, photographs, slides, research material and notes, course material, annual reports and drafts of his work. The fonds is divided into three (3) series.