The James Morrison papers are a collection of documents chiefly related to James Morrison's activities as a trader and merchant in Montreal. The papers also include some material related to Morrison's family, including legal documents and genealogical research conducted by his descendents. The documents in the James Morrison papers cover a period beginning 18 September 1651 and ending in approximately 1912, but focusing primarily on 1767 through 1800. The fonds represents Morrison's business dealings in Quebec, Ontario, the northern United States, and England, as well as his family life in Montreal and connections with relatives in Baltimore, Ontario, and Jamaica.

The papers are arranged into three series: 1 - Journals, 2 - Correspondence, and 3 - Financial and legal records. Documents in these series include a bound journal, correspondence, contracts, deeds of ownership, power of attorney, birth and marriage certificates, bills of sale, invoices, accounts, descriptions of political and military events, and genealogical notes.