The collection contains private records and papers relating to the medical and teaching career of Maude Abbott. It consists in large part of correspondence, 1894-1920, including family correspondence with, among others, her sister Alice Abbott, 1904-1919, and her brother Rev. Harry M. Babin, 1916-1920. Also included are manuscripts and drafts of articles and addresses; case reports; post-mortem records; glass slides and drawings; exhibit panels largely pertaining to her research on congenital heart disease; programmes of medical meetings, 1902-1937; reprints and papers relating to the history of medicine in Montreal and Quebec, as well as to the history of McGill, 1829-1936. In addition, there are photographs, some poems, an autobiographical sketch and a printed copy of her Classified and Annotated Bibliography of Sir William Osler's Publications, 1939, with corrections and annotations by W. W. Francis. Fonds also includes a draft of Abbott's letter to the Dean of Faculty of Medicine, McGill University, regarding admission (1889).

The fonds includes Dr. Archibald’s correspondence and reports pertaining to the Ministry of National Defence, 1940-1945; certificates and diplomas; and a photograph. The correspondents include family members, Dr. John McCrae and Sir William Osler. There is also a draft of a book on wound ballistics and gas gangrene; an Army Field Service book, 1916 and two notebooks on internal and external pathology, “matiere medicale et therapeutique,” and “medecine legale et toxicologie,” 1895.

The Sir William Osler Collection, distinct from the Bibliotheca, is an extensive archival holding of Osler's correspondence (including eighteen hundred original letters), daybooks, accounts, engagement books, legal documents, book invoices, membership certificates, notebooks, lectures, addresses, newspaper clippings, photographs, books with manuscript additions, and miscellaneous loose items formerly inserted into individual books in his library. The collection also contains various family papers, including correspondence of Lady Grace Revere Osler and Edward Revere Osler.