Fonds documents the Mallochs' activities related to their medical and literary work. The fonds contains notes, correpondence, commonplace books, account books, material related to publications, family memorabilia, scrapbooks, photographs, telegrams, postcards and certificates.

Fonds consists of personal letters between Howard family members and close relations (C. P. Howard, William Osler, Grace Osler, the Wright family etc.). Subjects range from wedding engagement congratulations for C. P. Howard and Otillie Wright, personal introductions from Grace Osler, to professional appointment letters. There are original photographs (as well as a few copies) of candid Osler family moments, formal family portraits, hospital photos of Osler at work, as well as several professional portraits of William Osler by prominent Montreal photographers. The fonds also includes miscellaneous reprints, booklets, and various other publication materials such as R. P. Howard's valedictory addresses to several graduating classes, personal copies of medical case studies, Olser's handwritten medical notes from 1875-1878, as well as original caricature sketches by Edward Revere Osler. In addition, there is a small photo album (in its own presentation box) with John Hopkins Hospital staff portraits (names included) from 1902-1903. The photo album is stamped "C.P.H." on the front cover.\nIncluded in the fonds are the following books: The Holy Bible (Oxford, 1912), The Poems of Edgar Allan Poe (Diamond Edition, New York, 1881), and Robert Bridges The Spirit of Man (Longmans Green and Co., London, 1916).

Fonds contains correspondence mostly between George Dock and Sir William Osler but also with Lady Osler, W.W. Francis and Archibald Malloch, from 1891 to 1919. The fonds includes 106 letters, originals and carbon copies.