The collection consists of documents pertaining to Dr. H. S. Birkett's medical activities, including 117 bound volumes of patient records (1889-1942), medical notebooks (1893-1896), bound RVH reports (1894-1938), RVH charts (1901-1920) and registers (1899-1917). There are also various letters addressed to Mr. and Mrs. Birkett, a manuscript, newspaper clippings, various degrees and medical association certificates, as well as photographs of H. S. Birkett's personal life and professional life at McGill and elsewhere. The collection also includes various artifacts collected by H. S. B, including military and medical memorabilia collected by H. S. Birkett.

The fonds illustrates Alexander MacDonald's work as a medical student and physician and includes photographs, a thank you card, and biographical notes by his granddaughter.

The fonds reflects Dr. Ferencz's friendship with the physician Harold N. Segall from the early 1960s until his death in 1990. It contains letters, cards, and postcards Dr. Ferencz received from Dr. Segall, as well as photographs of Dr. Segall and ephemera relating to the Segall-Gross lectures and various celebrations of Dr. Segall's life.

The fonds consists primarily of letters written during World War I to Drake's sister Daisy Molson and sister's husband, John Dunham Molson. Letters are accompanied by transcriptions and biographical material prepared by Martha E. McKenna. Also included are newspaper clippings dated 1915-1918 on Drake and the Canadian Army Medical Corps hospital run by McGill, one pocket notebook documenting Drake's time with the CAMC in France from 1915-1916, and a membership card to the Royal Club for Ladies from Beyond the Seas, dated 1919.

The fonds consists of textual records including proposal letters, guidelines, budget documents, and the six original VHS tapes made in 1984-85. Preservation copies of DVDs and mp4s made in 2016 are also included.

Fonds consists of personal letters between Howard family members and close relations (C. P. Howard, William Osler, Grace Osler, the Wright family etc.). Subjects range from wedding engagement congratulations for C. P. Howard and Otillie Wright, personal introductions from Grace Osler, to professional appointment letters. There are original photographs (as well as a few copies) of candid Osler family moments, formal family portraits, hospital photos of Osler at work, as well as several professional portraits of William Osler by prominent Montreal photographers. The fonds also includes miscellaneous reprints, booklets, and various other publication materials such as R. P. Howard's valedictory addresses to several graduating classes, personal copies of medical case studies, Olser's handwritten medical notes from 1875-1878, as well as original caricature sketches by Edward Revere Osler. In addition, there is a small photo album (in its own presentation box) with John Hopkins Hospital staff portraits (names included) from 1902-1903. The photo album is stamped "C.P.H." on the front cover.\nIncluded in the fonds are the following books: The Holy Bible (Oxford, 1912), The Poems of Edgar Allan Poe (Diamond Edition, New York, 1881), and Robert Bridges The Spirit of Man (Longmans Green and Co., London, 1916).

Fonds contains various certificates and awards received by Browne; photographs and slides; two official portraits; letters of Ms. W. Browne (sister) regarding Browne; Last Will and Testament; The Canadian Medical Hall of Fame Induction Ceremony VHS, and newspaper clippings.

The fonds contains ledgers, legal documents, permits, one scrapbook, and photographs.

The fonds contains fourteen notebooks kept by the Poisson family during their studies in medicine. The notebooks contain lecture notes and class notes on various topics in medicine taught by prominent professors such as, Jean Étienne and L. Landry, L. Simard, F.A.H. Larue, and J. Sewell.

The fonds contains correspondence related to the Osler Library and its holdings with people such as Maude Abbott, Edward Archibald, William B. Bean, Edward Horton Bensley, Archibald Malloch, Casey Wood, as well as John Farquhar Fulton, Keeper of the Medical History Collections at Yale University's library; the fonds also contains a typescript of talks by W.W. Francis (titled "Showman's Patter") about books and other items held in the Osler Library.