Fonds contains notes taken by Thomas McCrae between 1897 and 1904 at William Osler's clinics at the Johns Hopkins Hospital, Baltimore.

Fonds contains lecture notes taken by Robert Struthers at McGill Medical College in 1881-1882, including notes on Pathology, Surgery and Ophthalmology. Lecturers include Robert Palmer Howard, Sir Thomas Roddick and Sir William Osler. There is also a case report by Struthers. The fonds includes two notebooks and a case report.

Fonds shows Dr. Philip Franklin's relations and activities with Sir William Osler regarding the Post-Graduate Scheme in England and the American Hospital in England during WWI. The fonds contains letters, telegrams and an agenda and printed material regarding a meeting about the American Hospital.

The fonds documents the Osler Society's activities. The fonds contains lectures, dinner menus, list of speakers, newsletters, papers, posters and tape recordings.

The fonds contains the manuscript of his book William Osler : A Life in Medicine.

Fonds documents the Mallochs' activities related to their medical and literary work. The fonds contains notes, correpondence, commonplace books, account books, material related to publications, family memorabilia, scrapbooks, photographs, telegrams, postcards and certificates.

Fonds documents Dr. Lella's research activities while at McGill.

Fonds documents the Montreal years of H.V. Ogden and the ties he had with Sir William Osler. The fonds contains the correspondence of H.V. Ogden consisting of letters from May Francis and Marian Francis (Osborne), letters from George Cantlie, a letter from Dr. Robert Palmer Howard and a letter from Edmund J.A. Rogers.

Fonds shows Henry Beaumont Small's activities as a medical student through his admission cards for his complete medical formation. It contains 43 admission cards signed by or printed for the teachers, among them William Osler.

Fonds contains correspondence, including letters and postcards from Sir William Osler, clippings and two photographs.