Fonds contains notes taken by Thomas McCrae between 1897 and 1904 at William Osler's clinics at the Johns Hopkins Hospital, Baltimore.

Fonds consists of personal letters between Howard family members and close relations (C. P. Howard, William Osler, Grace Osler, the Wright family etc.). Subjects range from wedding engagement congratulations for C. P. Howard and Otillie Wright, personal introductions from Grace Osler, to professional appointment letters. There are original photographs (as well as a few copies) of candid Osler family moments, formal family portraits, hospital photos of Osler at work, as well as several professional portraits of William Osler by prominent Montreal photographers. The fonds also includes miscellaneous reprints, booklets, and various other publication materials such as R. P. Howard's valedictory addresses to several graduating classes, personal copies of medical case studies, Olser's handwritten medical notes from 1875-1878, as well as original caricature sketches by Edward Revere Osler. In addition, there is a small photo album (in its own presentation box) with John Hopkins Hospital staff portraits (names included) from 1902-1903. The photo album is stamped "C.P.H." on the front cover.\nIncluded in the fonds are the following books: The Holy Bible (Oxford, 1912), The Poems of Edgar Allan Poe (Diamond Edition, New York, 1881), and Robert Bridges The Spirit of Man (Longmans Green and Co., London, 1916).

Fonds contains lecture notes taken by Robert Struthers at McGill Medical College in 1881-1882, including notes on Pathology, Surgery and Ophthalmology. Lecturers include Robert Palmer Howard, Sir Thomas Roddick and Sir William Osler. There is also a case report by Struthers. The fonds includes two notebooks and a case report.

Fonds shows Dr. Philip Franklin's relations and activities with Sir William Osler regarding the Post-Graduate Scheme in England and the American Hospital in England during WWI. The fonds contains letters, telegrams and an agenda and printed material regarding a meeting about the American Hospital.

The fonds documents the Osler Society's activities. The fonds contains lectures, dinner menus, list of speakers, newsletters, papers, posters and tape recordings.

The fonds contains the manuscript of his book William Osler : A Life in Medicine.

The fonds contains materials that Dr. M. Entin collected for his biography of Dr. Archibald. Mainly include articles relate to tuberculosis, pancreatitis, wound healing, history of surgery, and scientific writing. It also includes letters from Edward Archibald to Mrs. Archibald, letters to Archibald from William Osler and Sir Henry Gray, addenda of Archibald's world journey in 1936, and articles by Archibald.

Some draft chapters of the biography of Dr. Archibald and research data for 100th Anniversary of Royal Victoria Hospital can also be found in the fonds.

Fonds documents the Mallochs' activities related to their medical and literary work. The fonds contains notes, correpondence, commonplace books, account books, material related to publications, family memorabilia, scrapbooks, photographs, telegrams, postcards and certificates.

The fonds consists of books, letters, documents, drafts, publications, photographs, and several artifacts collected by W. W. Francis and Marian Francis Kelen over the course of their lifetimes. Many books and documents relate to Sir William Osler and the Osler family including several personal letters, the Deed of Trust documents regarding the Bibliotheca Osleriana, drafts of Osler's works, and a wooden travelling trunk that belonged to Edward Revere Osler. The fonds also includes original poetry written by Marian Osborne, W. W. Francis, and Marian Francis Kelen.

Fonds documents Dr. Lella's research activities while at McGill.