The Penfield fonds consists of over eighty metres of Penfield's personal and professional records dating from his childhood up until his death in 1976, including during his career at the Montreal Neurological Institute. The materials in the fonds include photographs, correspondence, manuscripts and drafts of publications and speeches, research notes, glass slides, bound reports, films, and academic gowns.

The file contains correspondence with R.C. Featherstonhaugh regarding the field house reconstruction and the new wing of the Montreal Neurological Institute. This includes estimates, conception and cancellation as well as one architectural drawing.

The file contains miscellaneous correspondence and memorandums about the Ambulatory Care Centre Royal Victoria Hospital, 5th floor Montreal Neurological Institute, EVA Transformer, Radiology Department.

The file contains correspondence about the cost of care and services for the Department of Pensions and National Health Annex (specifically mentioning the Military Annex).

The file contains correspondence about the Military Annex transfer to the Montreal Neurological Institute including 2 aerial photographs, program, invitations list, and speech (possibly written by Wilder Penfield).

The file contains correspondence with Architects about the Military Annex (Featherstonhaugh) about plans, fittings, and alterations.

The file contains two reports, 'Effects of bombing on Hospital casualties', by E.H. Botterell and 'Report of command course', by Majors Hyland and Childe and Captain Hanson.

The file contains 2 complete sets (nos. 1-12) of Interim Reports (an incomplete set has been placed with photos in E/VN 3, being replaced by the 2 library copies).

The file contains 14 postcards of the environment around the Basingstoke Hospital; 17 snapshots, including some with Wilder Penfield, (duplicates of 2 in E/VN 3); 2 snapshots of pheasant's brain & lung; a photo of a portrait sketch of C. Russell; 3 official Candadian Medical Hospital press photos, meeting of Ryl Soc. Br. Neurol. Surg, Basingstoke Hospital.

The file contains a printed announcement of Penfield and Cone’s professional wartime services; 1 bound volume containing legends for the photographs in A/N 11-7/1; and a photocopy of R.C. Fetherstonhaugh’s ‘McGill University at War’ listing all those killed in action, killed on active service or died of wounds for 1939-1945.