Harry Mayerovitch was born on April 16, 1910, in Montreal, Quebec.

He was a Canadian architect, artist, illustrator, author, professor, and cartoonist. He received a Bachelor of Arts and his degree in architecture in 1933 at McGill University.
In the course of his long architectural partnership with Alan Bernstein and Lionel Mincoff, he designed many buildings in the Montreal area. Architecture projects were put on hold when Canada entered World War II. He turned his attention to painting, with one painting, a war-themed work entitled “Home Front”, exhibited at the Montreal Museum of Fine Arts.
He became artistic director of the National Film Board's Wartime Information Board’s Graphic Arts Division. From 1942 to 1944, he produced World War II propaganda posters, using the artist's signature "Mayo". After the war, he resumed work as an architect and became active in urban planning.

In 1965, he began to teach at McGill's School of Architecture and remained on faculty until his death. In 2000, his 90th birthday was marked with the planting of a magnolia tree in the School of Architecture's Centennial Garden. He was a member of the Order of Architects of Quebec, the Corporation of Urbanists of Quebec, the Canadian Institute of Planners, the Royal Canadian Academy of Arts, the Canadian Society of Graphic Arts, and was a Fellow of the Royal Architectural Institute of Canada.

In 1937, he married Lily Caplan. He died on April 16, 2004, in Montreal, Quebec.