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This group is an award-winning performing ensemble in its own right and performs on a regular basis, both at McGill and around the Montreal area.

The ensemble has released eight highly regarded CDs over the years and has performed with world-class visiting guest artists. The orchestra is dedicated to the performance of both traditional jazz masterworks and contemporary repertoire and regularly performs the music of Canadian composers and of McGill students and faculty.

McGill Group in Medical Genetics was formed in 1972 and was supported through funding by the Medical Research Council and subsequently by the Canadian Institutes for Health Research (CIHR) until 2009. The group originally formed in 1972 under the primary direction of Dr. F. Clarke Fraser and Dr. Charles Scriver and at the recommendation of Malcolm Brown, President of Canada’s Medical Research Council. During the latter half of the 20th century, medical genetics was a coalescing field, the development of which progressed rapidly during the 1960s and 1970s as clinicians sought to apply research into chromosomal abnormalities and biochemical genetics to the care and counseling of individual patients. The fourteen members of the McGill Group in Medical Genetics were: F. Clarke Fraser, Charles Scriver, Rima Rozen, David Rosenblatt, Reynold Gold, Leonard Pinsky, Emil Skamene, Peter Hechtman, Eric Shoubridge, Mark Trifiro, Andrew Karaplis, Robert MacKenzie, Roy Gravel, and Susie Tenenhouse. They represented medical specializations including teratology, biochemistry, population genetics, and endocrinology. Group members produced over 1,400 articles during the course of the group's history.