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The fonds consists mainly of a bound notebook that Mussen kept with notes on his experimental investigations. Includes mounted photographs of brain specimens and animal subjects. Fonds also contains loose manuscript notes and two overhead projector transparencies.

Fonds shows Alphonse Allard’s activities as a medical student at McGill University from 1863 to 1865. It contains seven admission cards autographed by the teachers and also a certificate from the College of Physicians and Surgeons of Lower Canada

The fonds illustrates Alexander MacDonald's work as a medical student and physician and includes photographs, a thank you card, and biographical notes by his granddaughter.