The collection consists of documents pertaining to Dr. H. S. Birkett's medical activities, including 117 bound volumes of patient records (1889-1942), medical notebooks (1893-1896), bound RVH reports (1894-1938), RVH charts (1901-1920) and registers (1899-1917). There are also various letters addressed to Mr. and Mrs. Birkett, a manuscript, newspaper clippings, various degrees and medical association certificates, as well as photographs of H. S. Birkett's personal life and professional life at McGill and elsewhere. The collection also includes various artifacts collected by H. S. B, including military and medical memorabilia collected by H. S. Birkett.

The fonds consists of Dr. Campbell's partially edited and unfinished autobiography, which he began writing in the 1960s and continued until the time of his death in 1970. The work covers the period from, approximately, 1831 to 1932. Additionally, the fonds includes the medal Dr. Campbell received for serving as Past President of the Montreal Medico Chirurgical Society, 1952-53.

Fonds contains William Wood Squire's manuscript of his thesis "Pathology and Treatment of some forms of Partial Paralysis" which won a prize as best thesis in medicine at McGill in 1864. The fonds includes a bound notebook and one loose illustration.

The fonds contains Roderick Stewart's research work and writing for his biography of Dr. Norman Bethune published as Bethune (1973) and The Mind of Norman Bethune (1977).

Fonds consists of a manuscript translation by Dr. Gruner of volume II of the Canon of Medicine of Avicenna dated 1957 and vocabulary indexes of Arabic names of Materia Medica, Latin-English names, Latin-Arabic equivalents, native names and others. These vocabularies were done in 1929-1930. It also contains three volumes of Dr. Gruner's research on cancer. This work was done through the Archibald Cancer Research Fund, from 1932 to 1946. In volume III, a printed address "A Vagabond Cruise Round Cancer" (1950) is inserted in the cover.