Sub-series A-2 contains miscellaneous correspondence concerning a wide variety of medical topics, and dating, for the most part, in the 1930s-1940s. This sub-series is comprised of 28 files (files no. 72 to 99), which are arranged alphabetically. The records in each file are arranged in reverse chronological order.

Sub-series A-1 contains professional correspondence concerning a wide variety of medical topics, and dating, for the most part, in the 1950s. This sub-series is comprised of 71 files (files no. 1 to 71), which are arranged alphabetically. The records in each file are arranged in reverse chronological order.

Series A contains correspondence concerning a wide variety of medical topics. The majority of this correspondence concerns Dr. Cone and his association with the Presbyterian Hospital, McGill University, the Royal Victoria Hospital and the Montreal Neurological Institute. Correspondence relating to the development of improved neurological instruments is also included in this series. Also includes obituaries of Dr. Cone.

The fonds illustrates Dr. Cone's work as a neurosurgeon and consists of correspondence, letters, articles, newspaper clippings, obituaries, photographs, slides, research material and notes, course material, annual reports, manuscripts, typescripts, annotations, published and unpublished manuscripts written by Dr. Cone, printed copies of articles, and patient files.