The collection consists of 3 scrapbooks assembled by Richard L. MacDonnell, and 1 McGill Dissection Room Record Book created and kept by MacDonnell from April 1883-1891. The scrapbooks contain notes, patient prescription information, reprints of various publications by MacDonnell, and lots of news clippings concerning various topics such as the history of Montreal, McGill University, the McGill faculty, Montreal General Hospital, and obituary notices. A second volume of dissection records (1896-1908) was compiled after MacDonnell's death, and can be found in the library catalogue.

The fonds consists of textual records including proposal letters, guidelines, budget documents, and the six original VHS tapes made in 1984-85. Preservation copies of DVDs and mp4s made in 2016 are also included.