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The fonds consists mainly of a bound notebook that Mussen kept with notes on his experimental investigations. Includes mounted photographs of brain specimens and animal subjects. Fonds also contains loose manuscript notes and two overhead projector transparencies.

Fonds contains two admission cards of Harry C. Cunningham for the year 1883, one for the course of Microscope in Medicine signed by Sir William Osler and one for a six month ticket to the Montreal General Hospital.

Fonds shows Henry Beaumont Small's activities as a medical student through his admission cards for his complete medical formation. It contains 43 admission cards signed by or printed for the teachers, among them William Osler.

Fonds documents the Montreal years of H.V. Ogden and the ties he had with Sir William Osler. The fonds contains the correspondence of H.V. Ogden consisting of letters from May Francis and Marian Francis (Osborne), letters from George Cantlie, a letter from Dr. Robert Palmer Howard and a letter from Edmund J.A. Rogers.

Fonds contains lecture notes taken by Robert Struthers at McGill Medical College in 1881-1882, including notes on Pathology, Surgery and Ophthalmology. Lecturers include Robert Palmer Howard, Sir Thomas Roddick and Sir William Osler. There is also a case report by Struthers. The fonds includes two notebooks and a case report.