A partial inventory of this collection reveals that it is largely composed of the scattered personal papers of the members of the Worthington Family, ca. 1833-1944, especially those of Edward Dagge Worthington and Arthur Norreys Worthington. The fonds also includes a few items pertaining to Edward Bruen Worthington and Asheton N. Worthington. It includes personal, business and professional correspondence; certificates, diplomas, tests, maps, sketchbooks, loose ledger sheets, testimonials, photographs and newspaper clippings. The greater part of the collection consists of the papers of Edward Dagge Worthington including correspondence related to his business affairs, medical career and family matters (1840-1883); medical certificates and diplomas, (1840-1847); two sketchbooks, (1840?); with caricatures of John Goodsir, Alexander Munro, Robert Knox and William Robertson; testimonials (1865, 1867); a resume of his education covering 1833-1843; newspaper clippings and photographs. The papers of Arthur Norreys Worthington are primarily correspondence describing his military activities in South Africa, 1900.

The fonds contains two sketchbooks of coloured sketches and shows William Arthur Johnson's activities in natural sciences and microscope work.

Fonds reflects Shirley Goodall's work as a medical illustrator on the service of various McGill physicians. The fonds consists chiefly of sketches in pencil on paper, medical illustrations mounted on board. Also includes reprints of journal articles where many of her illustrations were published.