Frederick Mackenzie was born on April 10, 1841, in Montreal, Quebec, the son of John Gordon Mackenzie (1796–1881), a wealthy dry goods merchant.

He was a lawyer and politician. He was educated at McGill University and was called to the bar in 1862. He was a captain in the militia and served during the Fenian raids (1866, 1870-1871). He was a secretary for the Church of England in Quebec and Montreal. Mackenzie represented Montreal West in the House of Commons of Canada from 1874 to 1875 as a Liberal member.

He died on July 2, 1889, in Boston, Massachusetts, and is buried in Montreal, Quebec.

Henry Oldham Mackenzie was born on November 21, 1825, in Terrebonne, Quebec, a son of Roderick Mackenzie (1761–1844) and Marie Louise Rachel Chaboillez (1786-1853). He died on May 30, 1879.

James Mackenzie was a younger brother of the Hon. Roderick McKenzie. He entered the service of the North West Company as a clerk in 1794. He was in the Athabaska department from 1795 to 1806. In 1802 he became a partner in the North West Company and was appointed to the King's Posts in the Lower St. Lawrence. Both his Athabaska journal of 1799-1800 and his account of the King's Posts in 1808 were published by Masson in his Bourgeois de la Compagnie du Nord-Ouest, Vol. II (1890). Although he retired from service at the King's Posts prior to 1821, he still maintained some connection there until his death in 1849.

John MacKenzie was born in 1794 in Athabasca, Alberta and died in 1871 in Terrebonne, Quebec. He was one of the nine children of Roderick Mackenzie of Terrebonne (1761-1844) and an unknown Chipewyan or Cree mother (1775-?). Mackenzie married Catherine Oldham in Montreal. He was a merchant, entrepreneur, and the Postmaster of Terrebonne.

Katherine (or Catherine) Mackenzie was born around 1740 in the Scottish Highlands, it is unknown when she died. She was the niece of Murdoch Mackenzie, 6th Laird of Fairburn. She married Alexander Mackenzie (1737-1789) of Achnaclerach.

Fur trader with the North West Company, he was based at Fort William following his apprenticeship and before his death in 1816.

Louisa MacKenzie was born in 1793 in Fort Chipewyan, on Lake Athabasca and died in 1833 in Michipicoten. She was the daughter of Roderick Mackenzie and an unknown Chipewyan woman. MacKenzie married Angus Bethune, a chief factor in the Hudson’s Bay Company in the early 1820s. They had six children.