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Duncan C. MacCallum was born at Ile aux Noix, Québec, and graduated in medicine from McGill in 1850. He was appointed Professor of clinical surgery at McGill in 1856, and of obstetrics, gynaecology and paediatrics in 1869. In 1883 he retired as Professor Emeritus. MacCallum was also on the staff of the Montreal General Hospital from 1867 to 1883, when he retired to private practice. He passed away in 1904.