Roderick Mackenzie was born in 1761 in Achiltibuie, Scotland, to Alexander Mackenzie of Achnaclerach and Catherine Mackenzie. Mackenzie moved to Quebec in 1784 and died in 1844 near Terrebonne, Quebec. Mackenzie’s family (brothers, cousins, and in-laws) were all involved in the fur trade, and he worked as a clerk and assistant for his first cousin Alexander Mackenzie. Mackenzie travelled to the northwest and established Fort Chipewyan and set up a library for the employees of the North West Company in Athabasca. While there, he married an unknown Indigenous woman “à la façon du pays” and had three to four children with her. His daughter Nancy, from this marriage, married a fur trader named John George McTavish. Nancy’s biography can be found linked to Mackenzie’s biography in the Dictionary of Canadian Biography, in which describes the typical life and treatment for Indigenous women at the time. Mackenzie served as lieutenant-colonel in the Terrebonne Militia and was appointed with the Legislative Council of Lower Canada. He was also appointed as Justice of the Peace for the “Indian Territories” (now known as south of the Great Lakes between the Mississippi and Ohio Rivers), and later for Montreal, Trois-Rivières, Gaspé, and Saint-François in Quebec. Mackenzie was a commissioner for various construction jobs (primarily of bridges and schools) and was a member of both the Literary and Historical Society of Quebec and the American Antiquarian Society and was a fellow of the Royal Society of Northern Antiquaries at Copenhagen. Mackenzie was accredited with the authorship of the introduction of his cousin Alexander Mackenzie’s book titled Voyages from Montreal, which gives an overall account of the history of the fur trade. He was also a member of the Beaver Club, a dining club for men who had influence in the fur trade.

Roderick Charles Mackenzie (or Charles Roderick Mackenzie) was born in 1816 and became a lawyer in Montreal.

Robert Mackenzie is a Professor Emeritus in the Department of Biochemistry, McGill University. Mackenzie recieved his PhD from Cornell University and did a postdoctoral fellowship at Berkeley. Mackenzie joined the McGill Group in Medical Genetics in 2001, where he was particularly interested in folate-mediation in mitochondrial DNA.

In January 1805, the estate of Simon McTavish leased the seigneury of Terrebonne for a period of 12 years to Henry Mackenzie (1781- 1832), an agent of the seigneury since 1803. Mackenzie then joined forces with McTavish's former partners, his brother Roderick Mackenzie (c. 1761-1844) and the lawyer turned merchant, Jacob Oldham (c. 1768-1824), to form a company that would evolve under the name Mackenzie, Oldham and Co. l’Île-des-Moulins had become a pre-industrial complex in Terrebonne managed by MacKenzie, Oldham, and Co., and equipped with a forge, a bakery, and various types of mills. The mills produced goods for sale but were also used by the citizens of Terrebonne to grind their flour and cut their wood. In 1832, the seigneury was put up for auction and was bought by Joseph Masson, a wealthy Montreal merchant.

Louisa MacKenzie was born in 1793 in Fort Chipewyan, on Lake Athabasca and died in 1833 in Michipicoten. She was the daughter of Roderick Mackenzie and an unknown Chipewyan woman. MacKenzie married Angus Bethune, a chief factor in the Hudson’s Bay Company in the early 1820s. They had six children.

Fur trader with the North West Company, he was based at Fort William following his apprenticeship and before his death in 1816.

Katherine (or Catherine) Mackenzie was born around 1740 in the Scottish Highlands, it is unknown when she died. She was the niece of Murdoch Mackenzie, 6th Laird of Fairburn. She married Alexander Mackenzie (1737-1789) of Achnaclerach.