Sir Edward Seaborne Clouston, 1st Baronet was born on May 9, 1849, in Moose Factory, Cochrane, Ontario. He was a Canadian banker and financier.

He received his education at the High School of Montreal and then worked for one year for the Hudson's Bay Company before commencing employment at the Bank of Montreal as a clerk in 1865. He became assistant general manager of the bank in 1887, general manager in 1890, and the first vice-president in 1906.

He was elected president of the Canadian Bankers Association on several occasions and, in this capacity, advised successive Canadian Ministers of Finance.

He served as vice-president of the Royal Trust Company and as a director of the Guarantee Company of North America, the Canadian Cottons, Ltd., the Canada Sugar Refining Company, the Ogilvie Flour Mills Company, and the Kaministikwia Power Company. He was chairman of the Canadian board of the Liverpool & London & Globe Insurance Company and the Mutual Life Insurance Company of New York.

In 1878, he married Annie Easton who was interested in charitable works. In 1895, she was elected vice-president of a committee to preserve Mount Royal Park. She was elected an office-bearer of the Woman's National Immigration Society. The family residences included a country house named Boisbriant at 170 Senneville Road in Senneville, Quebec, which was formerly owned by Sir John Abbott.

He died on November 23, 1912, in Montreal, Quebec.

Howard Rae Clouston received his B.A in 1909 and his M.D., C.M. in 1911 from McGill University. Apart from being a family practitioner, Dr. Clouston conducted research on a then little known hereditary disease, Ectodermal Dysplasia.