Fonds consists of correspondence with the pediatrician Dr. Alton Goldbloom of Montreal. It gives a picture of pediatrics and parental concerns at the time. The fonds contains 30 letters.

Fonds contains the manuscript of Dr. William Rees on the treatment of malaria, a lecture given before the Natural History Society of Montreal in the 1860s

Fonds contains the laboratory notebook used by R.D.H. Heard at the University of Toronto during his attempts to synthesize adrenaline and adrenaline-like substances in 1933.

Fonds contains two diaries for 1917 and 1918, and one address book of Dr. Robert Arthur Bowie during World War I. It includes 29 diaries written by his wife Pearl Blanche Bowie and by his daughter Margaret E. Bowie, from 1916 to 1951. In addition, there are a large number of photographs and negatives.

Fonds contains Whitwell's notebooks at McGill on lectures in Physiology, Pathology, Materia Medica, Practice of Medicine and Surgery. The lecturers include Drs. W. Fraser, W. Wright, A.F. Holmes and G.W. Campbell. The fonds includes six notebooks.

Fonds contains correspondence, including letters and postcards from Sir William Osler, clippings and two photographs.

Fonds contains the correspondence between Dr. Edmund Evan Simpson and the Osler Library Librarians, W.W. Francis and Cecile Desbarats, from 1942 to 1964. The fonds contains 21 letters, original and copies.

Fonds documents the Montreal years of H.V. Ogden and the ties he had with Sir William Osler. The fonds contains the correspondence of H.V. Ogden consisting of letters from May Francis and Marian Francis (Osborne), letters from George Cantlie, a letter from Dr. Robert Palmer Howard and a letter from Edmund J.A. Rogers.

Fonds documents John Thomas Basken's activities as a medical student. The fonds contains admission cards, certificates and one oath.

Fonds documents R. Cameron Stewart's research circa 1937 on the history of the first vaccinations against smallpox in Canada. The fonds contains letters, notes, two baptismal certificates and a newspaper clipping.