The collection consists of documents pertaining to Dr. H. S. Birkett's medical activities, including 117 bound volumes of patient records (1889-1942), medical notebooks (1893-1896), bound RVH reports (1894-1938), RVH charts (1901-1920) and registers (1899-1917). There are also various letters addressed to Mr. and Mrs. Birkett, a manuscript, newspaper clippings, various degrees and medical association certificates, as well as photographs of H. S. Birkett's personal life and professional life at McGill and elsewhere. The collection also includes various artifacts collected by H. S. B, including military and medical memorabilia collected by H. S. Birkett.

The Penfield fonds consists of over eighty metres of Penfield's personal and professional records dating from his childhood up until his death in 1976, including during his career at the Montreal Neurological Institute. The materials in the fonds include photographs, correspondence, manuscripts and drafts of publications and speeches, research notes, glass slides, bound reports, films, and academic gowns.

The fonds contains materials that Dr. M. Entin collected for his biography of Dr. Archibald. Mainly include articles relate to tuberculosis, pancreatitis, wound healing, history of surgery, and scientific writing. It also includes letters from Edward Archibald to Mrs. Archibald, letters to Archibald from William Osler and Sir Henry Gray, addenda of Archibald's world journey in 1936, and articles by Archibald.

Some draft chapters of the biography of Dr. Archibald and research data for 100th Anniversary of Royal Victoria Hospital can also be found in the fonds.

Fonds contains various certificates and awards received by Browne; photographs and slides; two official portraits; letters of Ms. W. Browne (sister) regarding Browne; Last Will and Testament; The Canadian Medical Hall of Fame Induction Ceremony VHS, and newspaper clippings.

The fonds illustrates Dr. Cone's work as a neurosurgeon and consists of correspondence, letters, articles, newspaper clippings, obituaries, photographs, slides, research material and notes, course material, annual reports, manuscripts, typescripts, annotations, published and unpublished manuscripts written by Dr. Cone, printed copies of articles, and patient files.

The fonds illustrates Dr. McNaughton’s work as a neurosurgeon and consists of correspondence, letters, articles, newspaper clippings, obituaries, photographs, slides, research material and notes, course material, annual reports and drafts of his work. The fonds is divided into three (3) series.

The fonds consists of Dr. Campbell's partially edited and unfinished autobiography, which he began writing in the 1960s and continued until the time of his death in 1970. The work covers the period from, approximately, 1831 to 1932. Additionally, the fonds includes the medal Dr. Campbell received for serving as Past President of the Montreal Medico Chirurgical Society, 1952-53.

The fonds illustrates Dr. Sowden's work in the field of rehabilitation medicine and consists of slides, photographs, and articles.

The fonds reflects Dr. Ferencz's friendship with the physician Harold N. Segall from the early 1960s until his death in 1990. It contains letters, cards, and postcards Dr. Ferencz received from Dr. Segall, as well as photographs of Dr. Segall and ephemera relating to the Segall-Gross lectures and various celebrations of Dr. Segall's life.

The fonds includes a copy of No. 3 Canadian General Hospital (McGill), 1914-1919 owned by Walter de M. Scriver and ephemera relating to Canadian General Hospital No. 3. It also contains a handwritten poem entitled "Tune of T'anks," composed by Scriver for his family and dated France, 1915.