Fonds shows Henry Beaumont Small's activities as a medical student through his admission cards for his complete medical formation. It contains 43 admission cards signed by or printed for the teachers, among them William Osler.

Fonds contains notes taken by Thomas McCrae between 1897 and 1904 at William Osler's clinics at the Johns Hopkins Hospital, Baltimore.

Fonds documents Dr. Lella's research activities while at McGill.

Fonds primarily documents Armstrong’s social life. They consist overwhelmingly of correspondence for the period 1909-1933. Letters from his professional colleagues, such as Sir William Osler, F.J. Shepard, Edward Archibald, William J. Mayo and others in the Mayo Clinic, are concerned largely with personal greetings, association memberships, or Medical Faculty business, particularly honorary degrees. Armstrong's non-medical correspondents include Lord Beaverbrook, Lord Atholstan, Sir Hugh Allan, Arthur Meighen, George Foster and Herbert Symonds. Topics include politics, Armstrong's war work and honours, some medicals matters, and personal news. Appended to this main series are obituaries and letters of sympathy to Armstrong's widow (1933), six photographs, including one of Armstrong in an operating room, and admission cards and diplomas from Armstrong's student years.