The fonds contains original and typescript letters, manuscript notes, newspaper clippings, journal extracts, reminiscences and more, assembled by Harvey Cushing chiefly between 1920 and 1924 during the course of his research for the biography of William Osler. For the biography, Cushing collected and retyped over 7500 pieces of Osler's correspondence, among which are some original letters.

The fonds is separated into three series: Manuscripts, Working Notes and Osler's Correspondence. It also contains photographs, annual reports, publications, clippings, one watercolor painting, one postcard. Osler's correspondence is further arranged in three subseries based chronologically.

The fonds consists of Robert Bell's student notebooks related to his medical studies in Surgery, Materia Medica, Practice of Medicine, Obstetrics, Physiology and Clinics at McGill University. The fonds also contains circular letters and medical advertisements. Inventory for acc.732 purchased from John Mappin in 1979 also included in fonds.

Fonds consists of autographed signed letter from Workman to John Auld of Montreal on Workman’s engraved stationery (Matthews lithographer), 25 November 1852.

Fonds shows Dr. Philip Franklin's relations and activities with Sir William Osler regarding the Post-Graduate Scheme in England and the American Hospital in England during WWI. The fonds contains letters, telegrams and an agenda and printed material regarding a meeting about the American Hospital.

Fonds shows the relationship between Thomas R. Boggs and William Henry Welch, one of the founders in the establishment of the Johns Hopkins Medical School in Baltimore. The fonds contains letters from Welch to Boggs, from 1910 to 1927 concerning A Century of Charades, a book of riddles by William Bellamy.

The fonds consists of Dr. Bensley's research notes and correspondence, particularly in relation to his publication McGill Medical Luminaries.

The fonds contains letters, 1948-1958, to and from Dr. W.W. Francis. It also includes two poems by Francis, and a letter from the Dean of the Faculty of Medicine regarding death of Francis in 1959.

Fonds consists of correspondence with the pediatrician Dr. Alton Goldbloom of Montreal. It gives a picture of pediatrics and parental concerns at the time. The fonds contains 30 letters.

Fonds contains correspondence, including letters and postcards from Sir William Osler, clippings and two photographs.

Fonds documents the Montreal years of H.V. Ogden and the ties he had with Sir William Osler. The fonds contains the correspondence of H.V. Ogden consisting of letters from May Francis and Marian Francis (Osborne), letters from George Cantlie, a letter from Dr. Robert Palmer Howard and a letter from Edmund J.A. Rogers.