Fonds documents R. Cameron Stewart's research circa 1937 on the history of the first vaccinations against smallpox in Canada. The fonds contains letters, notes, two baptismal certificates and a newspaper clipping.

The fonds consists chiefly of student notebooks kept by F. Clarke Fraser while an undergraduate at Acadia University during the late 1930s-1940. They represent a variety of subjects, including zoology, physics, mathematics, and biology. Two notebooks date from his Med IV year (1949-1950) at McGill University’s Faculty of Medicine, one with ophthalmology lab and clinical notes and reading and lecture notes, and one an obstetrical diary from the Montreal Maternity Hospital. Also included is a later reprint of an article (published 1957), loose notes, and a photograph of F. Clarke Fraser and a companion dining at the Montreal restaurant Au lutin qui bouffe, famous for its resident piglet, which restaurant-goers were often photographed holding and feeding.

The collection consists of seven volumes of Elliott's personal diaries, which were bound together, at his own expense, after their completion. These diaries cover the five-year period that Elliott spent serving overseas, primarily in England. The contents of the journals include handwritten entries, sketches and watercolours that were either executed in the pages of the diary or pasted in, and photographs, newspaper clippings, letters, playbills, menus and other paraphernalia that were also pasted into the diary. These serve to document both the development of the war and Elliott's personal experiences. The diaries are generally in chronological order although there are places, particularly in the last three volumes, where the diaries have been bound out of sequence.

The fonds also contains several folio sheets of photographs and clippings regarding Elliott's career.

Fonds contains the correspondence between Dr. Edmund Evan Simpson and the Osler Library Librarians, W.W. Francis and Cecile Desbarats, from 1942 to 1964. The fonds contains 21 letters, original and copies.

The fonds contains Dr. Ormrod's note books while an undergraduate and medical student at McGill.

Fonds contains a typewritten report signed by Martin to the Secretary of the Medical Board, Montreal General Hospital, dated February 1, 1944, in which Martin judges the Tumor Clinic at the MGH to be “Far below the standard set for similar clinics in American hospitals;” also includes envelope with address of Dr. Fraser B. Gurd.

Fonds shows Herbert Frederick Moseley's relations with his editor for his book "Shoulder Lesions". It contains an original manuscript with the publisher's annotations for the 1945 edition and another complete copy.

The fonds primarily reflects Pappius’s activities as a researcher at the Montreal Neurological Institute-Hospital (MNI/H): both her experimental research as such and various support activities, including academic publication, coordination of research projects with colleagues, and acquiring funding. It also contains much information about her leadership of the Clinical Neurochemistry Laboratory. The fonds contains smaller amounts of documentation regarding her activities as a professor at McGill University, her administrative roles at the MNI/H, and her participation in professional organizations, which reflects the smaller place that those roles occupied in her professional life.

The period of time best documented in the fonds spans the early 1980s to Pappius’s retirement in 1995. Correspondence with colleagues, mostly though not exclusively work-related, contains relatively more material from Pappius’s early career; although, here too, most of the material dates from the 1980s and after.

The main document types in the fonds related to Pappius’s research activities are experiment worksheets and printed tabular research data. Many of the research-related files contain negatives of autoradiographies, with a smaller number of photographic prints. Correspondence can be found in many series besides series F (Correspondence), as much of Pappius’s work was collaborative in nature.

The fonds is divided into eight series: (A) Research, (B) Academic events, (C) Teaching, (D) Administrative activities, (E) Professional organizations, (F) Correspondence, (G) Personal collections, and (H) Visual documents.

Fonds contains the case histories of Dr. S.E. Goldman submitted to the American College of Surgeons in February 1952, and include drawings and photographs. The fonds contains a bound book of case histories.

The collection consists of written correspondence between Dr. Clarence B. Farrar and Dr. Franklin G. Ebaugh concerning reproductive rights for victims of rape in relation to the case of a Denver woman who was the victim of rape in 1955. The woman ended up giving birth to a child after she was denied an abortion by doctors and lawyers. The collection also includes a three-page editorial titled "Legal Abortions" that cites Chapter 40, Article 2, Section 23 of the Colorado Revised Statutes 1953.