Series consists of a drawer of catalogue cards with information concerning most MNI Fellows from between the institute's opening to the 1970s. Much of this information consists of mailing addresses which were compiled in the late 1970s and early 1980s, and is thus likely no longer accurate. Many of the cards are also accompanied by photographs of the particular Fellow.

Series consists of notes produced by Dr. Penfield on books and articles he had read.

This series contains typed drafts and published sermons both written and delivered by Dr. Penfield, as well as published sermons by various Presbyterian/United Church ministers.

This series contains material concerning the "Sussex", an English Channel passenger steamer on which Dr. Penfield was travelling in 1916 when it was hit by a German torpedo.

This series consists of correspondence, notes, reports, and report drafts which were created and collected by Dr. Penfield as part of his travels to, and work in, Britain, the Middle East, and the Soviet Union for the National Research Council of Canada during the Second World War. (TR = Travels)

This series consists of the manuscripts, and related materials, of Dr. Penfield's published and unpublished writings.

Series consists of reports and notes collected and produced by Dr. Penfield as part of his work on committees of the National Research Council of Canada during the Second World War. The documents found in the series include American, British, and Canadian reports on different kinds of medical tests, as well as committee meeting minutes. (WP-CTEE = Wilder Penfield - Committees)

Series A contains correspondence concerning a wide variety of medical topics. The majority of this correspondence concerns Dr. Cone and his association with the Presbyterian Hospital, McGill University, the Royal Victoria Hospital and the Montreal Neurological Institute. Correspondence relating to the development of improved neurological instruments is also included in this series. Also includes obituaries of Dr. Cone.

Series B contains correspondence, research material and biographical information. It also includes teaching notes, lecture notes, typescripts on annual reports of both the Montreal Neurological Institute and the Royal Victoria Hospital, and statistical data of the Montreal Neurological Institute.

Series B is comprised of 62 files (files no. 107 to 169). The files are alphabetically arranged. The records in each file are arranged in reverse chronological order.