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The fonds consists of textual records and artifacts related to surgeon and researcher Dr. Charles R. Drew. It contains letters, artifacts, and a yearbook from Drew's time as a student at McGill University, including his notable achievements as a student athlete. These items include medals, a track meet program, an athletic shirt, and a yearbook. The fonds also contains invitations, pamphlets, and other ephemera related to tributes and honors awarded to Drew, including printed testimonials and materials associated with schools, lectures, and institutions named after him, such as the Charles R. Drew Postgraduate Medical School. These tributes and honors primarily recognize his contributions to medical science, but also encompass the program from his induction into the McGill Athletics Hall of Fame. Two letters in the fonds addressed to Drew's sister and his wife reflect on his accomplishments and include reminiscences from friends. Additionally, the fonds comprises five reprints of articles authored by Drew and two items concerning his career at Howard University and the Freedman's Hospital, including an outline for gathering a patient's medical history.

Leacock's papers comprise manuscripts of books, articles, and speeches written ca 1913-1937: included are Leacock's history of Montréal, and comic pieces such as "Too Much College", "The Stamp Album World", "Simple Stories of Success" and "Bed-Time, Stories for Grown-Up People". Correspondence covers the period ca 1915-1944. There are also newspaper articles by and about Leacock; book orders and related correspondence; manuscripts of articles and speeches about Leacock; and correspondence concerning donations to the Leacock Collection (Approximately 1948-1960).

Fonds consists of seven manuscript poems.

This consists of Cunliffe's manuscript of his History of the Dominion of Canada.

These consist of manuscripts of various Goldbloom's writings on paediatrics as well as various articles and speeches, 1929-1963, the manuscript of an unpublished short story titled "On a Monday Afternoon" and correspondence with Samuel Behrman, 1957-1965.