Gould's papers fall into two series. Family correspondence covers the years 1856 to 1860, when Joseph and his brother Charles were travelling in Europe, and consists of letters home from both young men, and their parents' replies. Manuscript music comprises two volumes of church anthems, with some organ music; some are original compositions by Gould and Samuel Warren. Related to this is Gould's brief manuscript account of the origin of the Mendelssohn Choir. Some family photographs are also included.

The collection consists of documents amassed by Roderick Mackenzie. Among the Masson manuscripts there are other series of letters; as well as journals kept by North-Westers and various business documents. Some of this material exists as originals; others are contemporary copies - the George Keith letters for example are contemporary copies on paper watermarked 1827. The collection also includes some duplicate texts - contemporary copies or later nineteenth-century copies that in some cases represent edited versions of the texts. Samuel Wilcocke's account of the death of Benjamin Frobisher exists in a draft original (or contemporary copy) and in a late nineteenth-century clean copy. Of course Benjamin Frobisher did not die in the dramatic circumstances as recorded by Wilcocke, but peacefully in Quebec City in 1821.

Collection consists of one bound manuscript notebook softbound in a piece of brown leather. The notebook dates chiefly from 1841 and was produced in St. Armand by Philip Luke. The notebook contains a title page that has been lettered, illustrated, and coloured by hand: A Latin Translation / by Philip Luke. St. Armand. 1841. Commenced April 4th. The text within this first portion of the notebook is Aesop's Fables in English and Latin on facing pages. The first part of the manuscript ends with "13. Horse and Ass" (Latin is incomplete) and "32. Widow and Servants" (Latin text missing). The following leaf contains two medical recipes: "A cure for a felon or whitlow," refering to an abscess or infection of the fingertip and consisting of a paste made from egg yolk, honey, turpentine spirits, camphor, and flour, and "A reciet for the inflammatory rheumatism," involving a wine-based tonic containing three types of bark, horseradish, brandy, and tar water. Following another blank leaf, a partial letter is found dated 1839. Philip Luke's text begins again in the latter part of the manuscript with a second coloured title page: "Dialogues and Declamations." There is also one loose note laid in dated 1809, a receipt for 100$.

These papers comprise a fair copy, for the press, of "Gale on Redeemable Annuities", 1816, as well as copies of letters to his son concerning the supplement to his "Treatise on the Nature and Principles of Redeemable Annuities", 1817. Apparently neither treatise was published.

The collection consists of four early Irish manuscripts assembled by the Montreal collector Edward Murphy as part of his private library. The manuscripts include a copy of The Midnight Court (Cúirt an mheán oíche) by Brian Merriman, the Life of St. Patrick by John Chambers, Tri Biorghaoithe an Bhais (Three shafts of death) by Geoffrey Keating, and a fragment of an Irish vocabulary (Nuadhfoclóir bogcruaideach).

Fonds consists of a late seventeenth-century manuscript containing a critical commentary on Machiavelli's The Price, created for the use of Agostino Cerretari.

Fonds consists of a manuscript of Mémoires de mathématique et de physique contenant un traité des épicycloïdes (published in Paris in 1674) and illustrated with mathematical diagrams.

Fonds consists of contemporary manuscript copies of various legal records and instruments relating to the Capacci family. Includes one manuscript written on parchment in pale brown ink, ruled in pale brown ink, and bound in full contemporary blind tooled calf with laid paper endpapers and remnants of ties on covers, as well as a smaller booklet, written on parchment glued into a laid paper wrapper. Documents appear to be dated between 1556 and 1583 and are written in Latin and Italian (sometimes alternating within document). The legal instruments appear chiefly related to the dowry of Orietta Capacci (the dowry is also referenced in an Italian note in a later hand (1650?) inside front cover). Some names found throughout the documents include Orietta Capacci (or Orietta de Capacci) and Annibale (or Anibal) Camillo de Capacci.

Fonds contains a manuscript, entitled "Remarks on the Osteology of Alexander Monro by himself", written by Dr. John George Bethune who transcribed an old damaged manuscript found in a trunk in the garret of the steam factory of Bethune's father in August 1848. The damaged manuscript was, according to Bethune, from one of three famous physicians, three successive generations of an Edinburgh family, who all bore the name Alexander Monro.

Fonds documents Dr. H.E. MacDermot's medical-historical activities. The fonds contains newspaper clippings, manuscript notes, photographs, lectures notes, and a draft of The MGH, the Years of Change.