The fonds illustrates Alexander MacDonald's work as a medical student and physician and includes photographs, a thank you card, and biographical notes by his granddaughter.

Fonds consists of photographs and other items that document the early career of Isadore Hirshberg while studying medicine at McGill University from 1909-1914, including 60 album-sized photographs, a framed group photograph of Hirshberg and Montreal General Hospital residents, Hirshberg's framed provincial medical certificate, and two certificates of residency. Subjects include Hirshberg and classmates; campus and student life; photographs of staff, doctors, and nurses in hospital settings, including two photographs of John McCrae at the Alexandra Hospital; and various views of McGill medical buildings and hospitals, including the new medical building at the time of construction in 1910, the Royal Victoria Hospital around 1910, and the Western Hospital in 1913. Two photographs features the medical school janitor James "King" Cook, a fixture of the school and a favorite with the students from the late 19th through the early 20th centuries. His wife was Frank Buller's housekeeper during Osler's time. Fonds also includes a large framed group photograph, Resident Medical Staff/Montreal General Hospital/1914-1915 by Wm. Notman & Son and Hirshberg's Quebec medical license issued by the College of Physicians and Surgeons of Quebec and dated July 1914. Descriptions of the photographs where present are in Hirshberg's hand except in cases in which there were additional descriptions in the album. These were copied in pencil on the verso of the related photograph.

The fonds consists of two bound volumes of notes on Endocrinology (some handwritten, some typed) from 1938-1939 and 1941-1942 while Masson was a PhD candidate at McGill University. Lectures given by: J. S. L. Browne, H. Selye, D. L. Thomson, C. F. Denstedt, C. Lyman Duff, C. P. Leblond, D. McEachern, R. L. Noble. Also included are three volumes of published works.

The fonds also consists of three bound volumes of Masson's published work from various medical journals (published in France, Canada, and USA) between 1932-1959. The articles are mostly in English, and some are in French.

The fonds documents John Bell's activities related to his medical studies at McGill in Surgery, Materia Medica and the Institutes of Medicine, as well as his work as a private physician in Montreal. The fonds consists of notebooks, a photocopy of his MS McGill medical thesis, letters from his personal and professional life, one of his medical kits, receipts from merchants, various subscriptions, societies and clubs. The fonds also contains various reprints of Bell's articles, including the 1878 article, "Case of Diphtheria, Acute Laryngeal Symptoms", as well as the City of Montreal's "Mortality of Montreal" – a list of all deaths in Montreal in January 1878.

Collection contains memorabilia relating to Dr. Robert Howard's student life at McGill University and of his career, from 1871 to 1888. Among the items are diplomas, photographs, newspaper clippings, a booklet from McGill University, a frame and a programme.

The Sir William Osler Collection, distinct from the Bibliotheca, is an extensive archival holding of Osler's correspondence (including eighteen hundred original letters), daybooks, accounts, engagement books, legal documents, book invoices, membership certificates, notebooks, lectures, addresses, newspaper clippings, photographs, books with manuscript additions, and miscellaneous loose items formerly inserted into individual books in his library. The collection also contains various family papers, including correspondence of Lady Grace Revere Osler and Edward Revere Osler.

Fonds contains lecture notes taken by Robert Struthers at McGill Medical College in 1881-1882, including notes on Pathology, Surgery and Ophthalmology. Lecturers include Robert Palmer Howard, Sir Thomas Roddick and Sir William Osler. There is also a case report by Struthers. The fonds includes two notebooks and a case report.

Fonds contains various certificates and awards received by Browne; photographs and slides; two official portraits; letters of Ms. W. Browne (sister) regarding Browne; Last Will and Testament; The Canadian Medical Hall of Fame Induction Ceremony VHS, and newspaper clippings.

The fonds consists of one 9 x 12" (23 x 30.5 cm) envelope containing a box of lecture tickets, testimonials and receipts collected by Dr. Walter J. McInnes MD 1865. The cards were issues between 1862 and 1865 and as is customary, they contain certification of Dr. McInnes' attendance and his assistance in a number of courses.