Fonds contains correspondence, including letters and postcards from Sir William Osler, clippings and two photographs.

The fonds contains original and typescript letters, manuscript notes, newspaper clippings, journal extracts, reminiscences and more, assembled by Harvey Cushing chiefly between 1920 and 1924 during the course of his research for the biography of William Osler. For the biography, Cushing collected and retyped over 7500 pieces of Osler's correspondence, among which are some original letters.

The fonds is separated into three series: Manuscripts, Working Notes and Osler's Correspondence. It also contains photographs, annual reports, publications, clippings, one watercolor painting, one postcard. Osler's correspondence is further arranged in three subseries based chronologically.

Fonds shows Henry Beaumont Small's activities as a medical student through his admission cards for his complete medical formation. It contains 43 admission cards signed by or printed for the teachers, among them William Osler.

Fonds documents the Montreal years of H.V. Ogden and the ties he had with Sir William Osler. The fonds contains the correspondence of H.V. Ogden consisting of letters from May Francis and Marian Francis (Osborne), letters from George Cantlie, a letter from Dr. Robert Palmer Howard and a letter from Edmund J.A. Rogers.

Fonds documents Dr. Lella's research activities while at McGill.

The fonds consists of books, letters, documents, drafts, publications, photographs, and several artifacts collected by W. W. Francis and Marian Francis Kelen over the course of their lifetimes. Many books and documents relate to Sir William Osler and the Osler family including several personal letters, the Deed of Trust documents regarding the Bibliotheca Osleriana, drafts of Osler's works, and a wooden travelling trunk that belonged to Edward Revere Osler. The fonds also includes original poetry written by Marian Osborne, W. W. Francis, and Marian Francis Kelen.

Letter from Lloyd Roberts, 11, St. John Street, Manchester, England, to William Osler. Letter inserted in "Religio Medici," edited by Lloyd Roberts, 1898. Roberts believes that Osler's copy of the "Religio" originally belonged to Coleridge. [See CUS417/4.12].