Series consists of miscellaneous material produced and collected by Dr. Penfield. This series includes art work, notes, and correspondence, as well as Dr. Penfield's academic robes and hats. This includes copies of the French 'Bulletin de l'Académie Royale de medecine', 'Bulletin de l'Académie nationale de medecine' and 3 editions of the Montreal La Lancette Canadienne journal. The series also includes less than 1 cm of photographs (found in file J 13-1), a framed diploma (file J 2-3) and selections for an exhibit from 1991 by William Feindel.

This series contains correspondence between Dr. Penfield and friends and colleagues, as well as social and professional institutions. The series' contents were found at the Montreal Neurological Institute in 2008, and thus, were not included with original correspondence series (Series C) of the Penfield Archive. The records in this series have been catalogued at the item level.

This series consists of objects or artifacts that belonged to Dr. Penfield.

This series contains the final drafts of Dr. Penfield's various published books.

Series consists of notes produced by Dr. Penfield on books and articles he had read.

This series contains typed drafts and published sermons both written and delivered by Dr. Penfield, as well as published sermons by various Presbyterian/United Church ministers.

This series contains material concerning the "Sussex", an English Channel passenger steamer on which Dr. Penfield was travelling in 1916 when it was hit by a German torpedo.

This series consists of correspondence, notes, reports, and report drafts which were created and collected by Dr. Penfield as part of his travels to, and work in, Britain, the Middle East, and the Soviet Union for the National Research Council of Canada during the Second World War. (TR = Travels)

This series consists of the manuscripts, and related materials, of Dr. Penfield's published and unpublished writings.