Papers consist of personal correspondence, including substantial family correspondence, diaries, journals, engagement books, ledgers, menus, manuscript poems, galley proofs, lecture notes, scrapbooks, and photographs. It includes correspondence, 1874-1935; a diary of Drummond's trip to Great Britain, 1902; dinner menus, 1902-1903; engagement books, 1902-1906; galley proofs, 1905-1911; Journal of Impressions kept at Savanna la Mar, Jamaica, Windsor and Montreal, 1903-1911; lecture notes taken at McGill, 1878-1882; ledgers containing financial entries and patients' accounts during Drummond's practice in Knowlton and Montreal, 1885-1889; notebooks containing manuscripts poems, drafts and clippings, 1894-1909; scrapbooks related to literary topics, including clippings about Drummond's public readings, and book reviews, 1854-1907 and scrapbooks related to Drummond's dogs, 1890-1907. There are also some papers of Mrs. W.H. Drummond, including a typescript of her Life of W.H. Drummond; and diaries recording her trips to United States and Canada, 1892, 1903.

The fonds documents mainly Babkin's professional interests in physiology, especially glandular secretions and the nervous system. The fonds contains correspondence; lecture notes; citations; research notes and papers, including manuscripts sent to him by his colleagues; reprints of scientific articles mainly in Russian; and material used in the preparation of the biography of Ivan Pavlov. The latter contains correspondence with Ivan Petrovich Pavlov and members of his family, 1923-1948; photographs and portraits; and an unabridged typescript copy of Parts 1-3 of Pavlov: a Biography, with manuscript corrections, 1943-1946.

Fonds consists of pamphlet entitled, “What to Eat to be Healthy” (Toronto: Canadian Medical Association and Canadian Life Insurance Officers Association, 1937), authored by Tisdall. Fonds also includes: typed letter signed from J. P. Crozer Griffith to Tisdall, Feb. 10, 1923, concerning a case on which Tisdall had consulted Griffith; autographed letter signed from Mrs. J. B. Gregory and Eliza J. Gregory, Aug. 2, 1920, agreeing to lease rental property to Tisdall; and autographed receipt signed from Mrs. J. B. Gregory acknowledging receipt of Tisdall’s rental payments.

The fonds contains original and typescript letters, manuscript notes, newspaper clippings, journal extracts, reminiscences and more, assembled by Harvey Cushing chiefly between 1920 and 1924 during the course of his research for the biography of William Osler. For the biography, Cushing collected and retyped over 7500 pieces of Osler's correspondence, among which are some original letters.

The fonds is separated into three series: Manuscripts, Working Notes and Osler's Correspondence. It also contains photographs, annual reports, publications, clippings, one watercolor painting, one postcard. Osler's correspondence is further arranged in three subseries based chronologically.

Fonds shows Dr. Philip Franklin's relations and activities with Sir William Osler regarding the Post-Graduate Scheme in England and the American Hospital in England during WWI. The fonds contains letters, telegrams and an agenda and printed material regarding a meeting about the American Hospital.

Fonds consists of autographed signed letter from Workman to John Auld of Montreal on Workman’s engraved stationery (Matthews lithographer), 25 November 1852.

The fonds consists of Robert Bell's student notebooks related to his medical studies in Surgery, Materia Medica, Practice of Medicine, Obstetrics, Physiology and Clinics at McGill University. The fonds also contains circular letters and medical advertisements. Inventory for acc.732 purchased from John Mappin in 1979 also included in fonds.

Fonds shows the relationship between Thomas R. Boggs and William Henry Welch, one of the founders in the establishment of the Johns Hopkins Medical School in Baltimore. The fonds contains letters from Welch to Boggs, from 1910 to 1927 concerning A Century of Charades, a book of riddles by William Bellamy.

The fonds contains letters, 1948-1958, to and from Dr. W.W. Francis. It also includes two poems by Francis, and a letter from the Dean of the Faculty of Medicine regarding death of Francis in 1959.

The collection contains private records and papers relating to the medical and teaching career of Maude Abbott. It consists in large part of correspondence, 1894-1920, including family correspondence with, among others, her sister Alice Abbott, 1904-1919, and her brother Rev. Harry M. Babin, 1916-1920. Also included are manuscripts and drafts of articles and addresses; case reports; post-mortem records; glass slides and drawings; exhibit panels largely pertaining to her research on congenital heart disease; programmes of medical meetings, 1902-1937; reprints and papers relating to the history of medicine in Montreal and Quebec, as well as to the history of McGill, 1829-1936. In addition, there are photographs, some poems, an autobiographical sketch and a printed copy of her Classified and Annotated Bibliography of Sir William Osler's Publications, 1939, with corrections and annotations by W. W. Francis. Fonds also includes a draft of Abbott's letter to the Dean of Faculty of Medicine, McGill University, regarding admission (1889).